58253-27-3
（5-羟基-1-(4-羟基-3-甲氧基-环己基)癸烷-3-酮,Gingerol）
5-羟基-1-(4-羟基-3-甲氧基-环己基)癸烷-3-酮
Gingerol
58253-27-3
C18H28O4
308.41252
名称和标识符
| InChIKey | ONQQLFWDTJJQKU-UHFFFAOYSA-N |
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| Inchi | InChI=1S/C17H32O4/c1-3-4-5-6-14(18)12-15(19)9-7-13-8-10-16(20)17(11-13)21-2/h13-14,16-18,20H,3-12H2,1-2H3 |
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| SMILES | CCCCCC(CC(=O)CCC1CCC(C(C1)OC)O)O |
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别名信息
- 中文别名 -
- 5-羟基-1-(4-羟基-3-甲氧基-环己基)癸-3-酮
- 5-羟基-1-(4-羟基-3-甲氧基-环己基)癸烷-3-酮
- 英文别名 -
- Gingerol
- 5-HYDROXY-1-(4-HYDROXY-3-METHOXY-CYCLOHEXYL)DECAN-3-ONE
- NS00124116
- 58253-27-3
- 5-Hydroxy-1-(4-hydroxy-3-methoxycyclohexyl)decan-3-one
物化性质
实验特性
| 沸点 | 453 °C at 760 mmHg |
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| 闪点 | 159 °C |
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| 密度 | 1.0713 |
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计算特性
| 精确分子量 | 300.23006 |
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| 氢键供体数量 | 2 |
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| 氢键受体数量 | 4 |
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| 可旋转化学键数量 | 10 |
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| 同位素质量 | 300.23006 |
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| 重原子数量 | 21 |
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| 复杂度 | 293 |
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| 同位素原子数量 | 0 |
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| 确定原子立构中心数量 | 0 |
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| 不确定原子立构中心数量 | 4 |
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| 确定化学键立构中心数量 | 0 |
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| 不确定化学键立构中心数量 | 0 |
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| 共价键单元数量 | 1 |
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| 疏水参数计算参考值（XlogP） | 2.3 |
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| 拓扑分子极性表面积 | 66.8 |
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相关文献
- 1. A recent update on the multifaceted health benefits associated with ginger and its bioactive components
Run-Hui Ma,Zhi-Jing Ni,Yun-Yang Zhu,Kiran Thakur,Fan Zhang,Yuan-Yuan Zhang,Fei Hu,Jian-Guo Zhang,Zhao-Jun Wei Food Funct. 2021 12 519 - 2. Medicinal chemistry inspired by ginger: exploring the chemical space around 6-gingerol
Sara Hassan Hassan Ahmed,Tímea Gonda,Attila Hunyadi RSC Adv. 2021 11 26687 - 3. 6-Gingerol modulates proinflammatory responses in dextran sodium sulfate (DSS)-treated Caco-2 cells and experimental colitis in mice through adenosine monophosphate-activated protein kinase (AMPK) activation
Kuei-Wen Chang,Cheng-Yi Kuo Food Funct. 2015 6 3334 - 4. Synergistic effect of quercetin and 6-gingerol treatment in streptozotocin induced type 2 diabetic rats and poloxamer P-407 induced hyperlipidemia
Yi Shao,Yao Yu,Cheng Li,Jing Yu,Rongrong Zong,Chonggang Pei RSC Adv. 2016 6 12235 - 5. Electrochemical detection and quantification of gingerol species in ginger (Zingiber officinale) using multiwalled carbon nanotube modified electrodes
Korbua Chaisiwamongkhol,Kamonwad Ngamchuea,Christopher Batchelor-McAuley,Richard G. Compton Analyst 2016 141 6321 - 6. 6-Gingerol mitigates nutritional steatohepatitis through regulating key genes related to oxidative stress, inflammation and fibrogenesis
Thing-Fong Tzeng,Shorong-Shii Liou,I.-Min Liu RSC Adv. 2014 4 61427 - 7. Vasculoprotective effects of ginger (Zingiber officinale Roscoe) and underlying molecular mechanisms
Chao Li,Jie Li,Feng Jiang,Nikolay T. Tzvetkov,Jaroslaw O. Horbanczuk,Yunlun Li,Atanas G. Atanasov,Dongdong Wang Food Funct. 2021 12 1897 - 8. 6-Gingerol-derived semisynthetic analogs mitigate oxidative stress, and reverse acrylamide induced neurotoxicity in zebrafish
Tamilvelan Manjunathan,Ajay Guru,B. Haridevamuthu,Rambabu Dandela,Jesu Arokiaraj,Pushparathinam Gopinath New J. Chem. 2023 47 10488 - 9. Effect of alginate coating enriched with 6-gingerol on the shelf life and quality changes of refrigerated red sea bream (Pagrosomus major) fillets
Luyun Cai,Yanbo Wang,Ailing Cao,Yanfang Lv,Jianrong Li RSC Adv. 2015 5 36882 - 10. Cross-talk between 10-gingerol and its anti-cancerous potential: a recent update
Fang Zhang,Kiran Thakur,Fei Hu,Jian-Guo Zhang,Zhao-Jun Wei Food Funct. 2017 8 2635
